diff --git a/source/framework/core/src/TRestDataSet.cxx b/source/framework/core/src/TRestDataSet.cxx
index 22ba8334a..321e090f6 100644
--- a/source/framework/core/src/TRestDataSet.cxx
+++ b/source/framework/core/src/TRestDataSet.cxx
@@ -992,6 +992,7 @@ void TRestDataSet::Export(const std::string& filename, std::vector<std::string>
         fDataFrame.Snapshot("AnalysisTree", filename);
 
         TFile* f = TFile::Open(filename.c_str(), "UPDATE");
+        TRestTools::PreserveStreamerInfos(f);
         std::string name = this->GetName();
         if (name.empty()) name = "mock";
         this->Write(name.c_str());
diff --git a/source/framework/core/src/TRestProcessRunner.cxx b/source/framework/core/src/TRestProcessRunner.cxx
index 2ff4d4ff0..6578ccca7 100644
--- a/source/framework/core/src/TRestProcessRunner.cxx
+++ b/source/framework/core/src/TRestProcessRunner.cxx
@@ -891,6 +891,7 @@ void TRestProcessRunner::FillThreadEventFunc(TRestThread* t) {
                 fRunInfo->SetNFilesSplit(fNFilesSplit);
                 if (fOutputDataFile->GetName() != fOutputDataFileName) {
                     auto Mainfile = std::unique_ptr<TFile>{TFile::Open(fOutputDataFileName, "update")};
+                    TRestTools::PreserveStreamerInfos(Mainfile.get());
                     WriteProcessesMetadata();
                     Mainfile->Write(0, TObject::kOverwrite);
                     Mainfile->Close();
diff --git a/source/framework/core/src/TRestRun.cxx b/source/framework/core/src/TRestRun.cxx
index af011ab61..5647e37bf 100644
--- a/source/framework/core/src/TRestRun.cxx
+++ b/source/framework/core/src/TRestRun.cxx
@@ -1020,6 +1020,10 @@ TFile* TRestRun::MergeToOutputFile(vector<string> filenames, string outputfilena
 
     // write metadata into the output file
     fOutputFile = new TFile(fOutputFileName, "update");
+    // Without this, closing the file would keep only the StreamerInfos of the classes
+    // streamed during this metadata session, wiping the event-class StreamerInfos
+    // written by the merge above (see TRestTools::PreserveStreamerInfos)
+    TRestTools::PreserveStreamerInfos(fOutputFile);
     RESTDebug << "TRestRun::FormOutputFile. Calling WriteWithDataBase()" << RESTendl;
     this->WriteWithDataBase();
 
@@ -1060,6 +1064,7 @@ TFile* TRestRun::UpdateOutputFile() {
         if (fOutputFile->IsOpen()) {
             fOutputFile->ReOpen("update");
         }
+        TRestTools::PreserveStreamerInfos(fOutputFile);
 
         fOutputFile->cd();
 
diff --git a/source/framework/tools/inc/TRestTools.h b/source/framework/tools/inc/TRestTools.h
index 649df089b..f499ff3c1 100644
--- a/source/framework/tools/inc/TRestTools.h
+++ b/source/framework/tools/inc/TRestTools.h
@@ -57,6 +57,8 @@ EXTERN_DEF std::string REST_USER_PATH;
 EXTERN_DEF std::string REST_TMP_PATH;
 EXTERN_DEF std::map<std::string, std::string> REST_ARGS;
 
+class TFile;
+
 /// A generic class with useful static methods.
 class TRestTools {
    public:
@@ -115,6 +117,8 @@ class TRestTools {
     template <typename T>
     static int ExportBinaryTable(std::string fname, std::vector<std::vector<T>>& data);
 
+    static void PreserveStreamerInfos(TFile* file);
+
     static Int_t isValidFile(const std::string& path);
     static bool fileExists(const std::string& filename);
     static bool isRootFile(const std::string& filename);
diff --git a/source/framework/tools/src/TRestTools.cxx b/source/framework/tools/src/TRestTools.cxx
index 44ef9b01b..7be7b1529 100644
--- a/source/framework/tools/src/TRestTools.cxx
+++ b/source/framework/tools/src/TRestTools.cxx
@@ -43,9 +43,11 @@
 ///
 #include "TRestTools.h"
 
+#include <TArrayC.h>
 #include <TClass.h>
 #include <TFile.h>
 #include <TKey.h>
+#include <TStreamerInfo.h>
 #include <TSystem.h>
 #include <TUrl.h>
 
@@ -713,6 +715,49 @@ int TRestTools::ReadCSVFile(std::string fName, std::vector<std::vector<Float_t>>
     return ReadASCIITable(fName, data, skipLines, ",");
 }
 
+///////////////////////////////////////////////
+/// \brief Re-tag the StreamerInfos already stored in a file opened in UPDATE mode,
+/// so that they survive the session.
+///
+/// When a ROOT file is closed, TFile::WriteStreamerInfo() REPLACES the StreamerInfo
+/// record of the file, keeping only the infos of the classes streamed during that
+/// session. An UPDATE session that only adds metadata (e.g. the reopen done by
+/// TRestRun::MergeToOutputFile after merging the threads' output) therefore wipes
+/// the StreamerInfos of the event classes written earlier. Without them, ROOT
+/// cannot apply schema evolution when the class definitions change, and old files
+/// become unreadable (see rest-for-physics/detectorlib#125).
+///
+/// Calling this method right after opening a file in UPDATE mode marks every
+/// StreamerInfo already present in the file to be written out again on close.
+///
+void TRestTools::PreserveStreamerInfos(TFile* file) {
+    if (file == nullptr || !file->IsOpen() || !file->IsWritable()) return;
+    TArrayC* classIndex = file->GetClassIndex();
+    if (classIndex == nullptr) return;
+
+    std::unique_ptr<TList> infos(file->GetStreamerInfoList());
+    if (infos == nullptr) return;
+    infos->SetOwner(kTRUE);
+
+    TIter next(infos.get());
+    TObject* obj;
+    while ((obj = next())) {
+        auto info = dynamic_cast<TStreamerInfo*>(obj);
+        if (info == nullptr) continue;
+        TClass* cl = TClass::GetClass(info->GetName());
+        if (cl == nullptr) continue;
+        auto current = dynamic_cast<TStreamerInfo*>(cl->GetStreamerInfo(info->GetClassVersion()));
+        if (current == nullptr) continue;
+        // Same marking as the (deprecated) TStreamerInfo::TagFile: flag the class
+        // so that TFile::WriteStreamerInfo includes it when the file is closed
+        const Int_t number = current->GetNumber();
+        if (number > 0 && number < classIndex->GetSize()) {
+            classIndex->fArray[number] = 1;
+            classIndex->fArray[0] = 1;
+        }
+    }
+}
+
 ///////////////////////////////////////////////
 /// \brief Returns true if the file with path filename exists.
 ///