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/*
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Nextflow config file for running minimal tests
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Defines input files and everything required to run a fast and simple pipeline test.
Use as follows:
nextflow run nf-cmgg/smallvariants -profile test,<docker/singularity> --outdir <OUTDIR>
----------------------------------------------------------------------------------------
*/
process {
resourceLimits = [
cpus: 4,
memory: '15.GB',
time: '1.h'
]
}
params {
config_profile_name = 'Test profile'
config_profile_description = 'Minimal test dataset to check pipeline function'
// Input data
input = "${projectDir}/assets/samplesheet.csv"
// Genome references
igenomes_ignore = true
custom_config_base = null
// References
fasta = "https://github.com/nf-cmgg/test-datasets/raw/smallvariants/data/genomics/homo_sapiens/genome/hg38_chr21_22000000_23000000.fasta"
fai = "https://github.com/nf-cmgg/test-datasets/raw/smallvariants/data/genomics/homo_sapiens/genome/hg38_chr21_22000000_23000000.fasta.fai"
dict = "https://github.com/nf-cmgg/test-datasets/raw/smallvariants/data/genomics/homo_sapiens/genome/hg38_chr21_22000000_23000000.dict"
elfasta = "https://github.com/nf-cmgg/test-datasets/raw/smallvariants/data/genomics/homo_sapiens/genome/hg38_chr21_22000000_23000000.elfasta"
sdf = "https://github.com/nf-cmgg/test-datasets/raw/smallvariants/data/genomics/homo_sapiens/genome/hg38_chr21_22000000_23000000_sdf.tar.gz"
strtablefile = "https://github.com/nf-cmgg/test-datasets/raw/smallvariants/data/genomics/homo_sapiens/genome/hg38_chr21_22000000_23000000.strtable.zip"
ped = "https://github.com/nf-cmgg/test-datasets/raw/smallvariants/data/genomics/homo_sapiens/genome/test_dots.ped"
msi_baseline = "https://github.com/nf-cmgg/test-datasets/raw/smallvariants/data/genomics/homo_sapiens/genome/msi_subset.baseline.list"
somalier_sites = "https://github.com/brentp/somalier/files/3412456/sites.hg38.vcf.gz"
expansionhunter_catalogue = "https://github.com/nf-cmgg/test-datasets/raw/refs/heads/smallvariants/data/genomics/homo_sapiens/genome/variant_catalog.json"
// Pipeline specific parameters
filter = true
annotate = false // This takes too long for a quick test run (unless you manually give the annotation references)
gemini = true
scatter_count = 2
validate = true
add_ped = true
vep_chunk_size = 10000
normalize = true
vep_merged = false
// VCFanno
vcfanno = true
vcfanno_config = "${projectDir}/assets/vcfanno.toml"
vcfanno_resources = "https://github.com/brentp/vcfanno/raw/master/example/exac.vcf.gz;https://github.com/brentp/vcfanno/raw/master/example/exac.vcf.gz.tbi"
}