Gene scores should not be displayed in cases where there no contributing variants for any MOI. Investigate cases where allelic state is ./1 as this can produce a gene score for AR and AD as Jannovar might be quite permissive.
e.g. in the case of a single ./1 variant in FOXC1 Exomiser the AD gene score is satisfied with a single hit, but the AR score should not appear, in the HTML and should not appear as a nonContributing variant in the parquet/TSV. i.e. ./1 should not be considered as compatible with AR (homozygous).
In the FOXC1 case there are hits to a mouse phenotype which is considered as a hit for AR but the only variant is the ./1 variant which is non-contributing then the MOI should be reported as 'ANY'
Gene scores should not be displayed in cases where there no contributing variants for any MOI. Investigate cases where allelic state is ./1 as this can produce a gene score for AR and AD as Jannovar might be quite permissive.
e.g. in the case of a single ./1 variant in FOXC1 Exomiser the AD gene score is satisfied with a single hit, but the AR score should not appear, in the HTML and should not appear as a nonContributing variant in the parquet/TSV. i.e. ./1 should not be considered as compatible with AR (homozygous).
In the FOXC1 case there are hits to a mouse phenotype which is considered as a hit for AR but the only variant is the ./1 variant which is non-contributing then the MOI should be reported as 'ANY'